Patient values
Normal range 135–145 mmol/L
Corrects sodium for hyperglycaemia-driven dilution
Euvolaemic work-up — as results come back
Possible drivers (tick any that apply)
Drug history: SSRI, carbamazepine, antipsychotic, PPI, cytotoxic, opiate, NSAID
Recent CNS event: stroke, haemorrhage, infection, trauma, psychosis
Pulmonary disease: pneumonia, TB, COPD/asthma exacerbation
Recent surgery, significant pain, or nausea
High low-solute fluid intake (excess water, beer, "tea and toast" diet)
Malignancy red flags: smoking history, weight loss, haemoptysis, lymphadenopathy
Family/personal history of endocrine tumours (parathyroid, pituitary, pancreatic, medullary thyroid)
Severe symptoms (any one → emergency)
Reduced consciousness (GCS ≤8) / coma
Seizures
Cardiorespiratory distress / arrest
Vomiting
Moderately severe symptoms
Confusion
Headache
Nausea without vomiting
Admission risk flags
Known/likely fall >10 mmol/L in <48h
Possible adrenal insufficiency
Recent intercurrent illness (chest infection / UTI / GI upset)